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Av. Diabetol. 2006;22(4):278-283

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Characterization of a cohort of type 1 diabetes patients treated at Internal Medicine Service of Costa Rica

Original Articles - Vol.22 N.4  October-December 2006
B. Hasbum-Fernández1, S. Salazar2, I. Martínez3, C. Arguedas-Chaverri4

 Author Affiliations


Type 1 diabetes is a rare disease in Costa Rica. Little is known about the metabolic control and the natural history of these patients after the pediatric age. During the follow-up`, patients were examined regularly 3-4 times per year. For their diagnosis and treatment, ADA guidelines were used. All the information was taken from the clinical files. Eighty-six patients, 46 women (53.5%) were followed. The mean age was 20.6 ± 5.4 years, with 52,3% of them between 10-19 years of age. Mean BMI was 24.8 ± 3.7 kg/m2 (range 17.7-36.7 kg/m2), being only 9.3% obese (BMI >30 kg/m2). Mean blood pressure was 116/72 mmHg. Age at diagnosis was 9.9 ± 3.9 years (range 1-22 years), with a time from diagnosis of 10.7 ± 5.7 years (range 1-24.6 years). Relating to metabolic control, mean HbA1c was 8.2 ± 2.1% (15% with HbA1c <6.5%; 23% with HbA1c between 6.5-7.4%, 39% with HbA1c between 7.5-9% and 22% with HbA1c >9%). With respect to the treatment, a total daily dose of 74.8 ± 24.2 IU/day were used employing by the majority of patients (95%) multiple daily injections. Most of them (98%) used human regular insulin and NPH insulin. As chronic complications, a high proportion of patients (82.5%) had proteinuria (mean UAE 118.6 mg/24h), whereas only 9.3% had diabetic retinopathy and 3.5% had diabetic neuropathy. In conclusion, metabolic control of type 1 diabetes in Costa Rica seems to be similar to what has been described in the literature worldwide. The high proportion of patients having diabetic nephropathy needs to be reevaluated in future studies to determinate the real prevalence of this complication in our patients.


Correspondencia: Dr. Benhard Hasbum-Fernández. Servicio de Medicina Interna. Hospital México.
La Uruca. San José (Costa Rica).
Correo electrónico:


microvascular complications diabetes in Costa Rica type 1 diabetes mellitus diabetic nephropathy


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